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Title: Social Sciences/Archaeology/Topics/Bioarchaeology - Ancient DNA May be Misleading Scientists From News in Science. Ancient DNA in skeletons has a tendency to show damage in a particular region resulting in misleading genetic data and mistaken conclusions about the origin of the skeleton Brit
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Ancient DNA may be misleading scientists

Tuesday, 18 February 2003  test tubes Dating skeletal material with DNA may not be as acurate as thought Ancient DNA in skeletons has a tendency to show damage in a particular region, resulting in misleading genetic data and mistaken conclusions about the origin of the skeleton, British scientists said. A group of researchers at the Henry Wellcome Ancient Biomolecules Centre of the University of Oxford, in Britain, made the finding while studying Viking specimens. They found that about half of the specimens had DNA that suggested they were of Middle Eastern origin. But more detailed analysis revealed that many of the genetic sequences in the double helix molecule, which carries the genetic information of every individual, were damaged at a key base that separates European sequences from Middle Eastern genetic types - damage which made the skeletons appear to have originated in the Levant.The results are published in the February 2003 issue of the American Journal of Human Genetics.Damage events appear to be concentrated in specific 'hotspots', indicating that a high proportion of DNA molecules can be modified at the same point. These hotspots appear to be in positions that also differ between different human groups. In other words, the DNA damage discovered affects the same genetic positions as evolutionary change. "Now that this phenomenon has been recognised, it is possible to survey the ancient sequences for damage more accurately, and determine the correct original genetic type - open the way for more reliable future studies," said Professor Alan Cooper, director of the centre. Cooper has hopes the finding may have implications for future research. "It also appears that we can use damage cause after death to examine how DNA damage occurs during life - a completely unanticipated, and somewhat ironic result," he said. "Potentially this allows us to get uniquely separate views of the two major evolutionary processes, mutation and selection." Danny Kingsley - ABC Science Online Related Stories Planet of the apes, News in Science 12 Jul 2001 "Out of Africa" in Asia, News in Science 11 May 2001 Neanderthals & modern humans may have interbred, News in Science 5 Apr 2001 More News Health & Medical • Environment & Nature • Space & Astronomy • Being Human • Ancient Worlds • Innovation & Technology • Science News Archives PrintPrint EmailEmail a friend | Email us ˆ top | Back to latest news    All Science News  Health & Medical  Environment & Nature  Space & Astronomy  Ancient Worlds  Innovation & Technology news Brightest supernova died six times Rainbows to give computers some oomph Monkey embryonic stem cells a world first Search News in Science News Archive Previous news stories Science Features Ibis invasion The secret life of water rats Science by Topic Ancient Worlds DNA & Genetics Sex & Relationships >> More topics Email List Join our email list Email address: more info >> About Us News in Science The Lab   contact | about | sitemap | search | email us the Lab - ABC Science Online thelab@your.abc.net.au ©2008 ABC | Privacy Policy ABC Online      
 

From

News

in

Science.

Ancient

DNA

in

skeletons

has

a

tendency

to

show

damage

in

a

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region

resulting

in

misleading

genetic

data

and

mistaken

conclusions

about

the

origin

of

the

skeleton

Brit

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From News in Science. Ancient DNA in skeletons has a tendency to show damage in a particular region resulting in misleading genetic data and mistaken conclusions about the origin of the skeleton Brit

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